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Calcium Oxalate in Biological Systems

Editor - Saeed R. Khan, Ph.D., Department of Pathology and Laboratory Medicine, University of Florida, Gainesville

Written by leaders in their fields, Calcium Oxalate in Biological Systems comprehensively discusses current information about the importance of this compound in animals, plants, fungi, and microorganisms. Both in vivo and in vitro methods of crystallization as well as crystallization systems are discussed. Researchers who pioneered the field contribute their invaluable knowledge for the first time about oxalate bacteria and their importance. This is an essential reference for both plant and animal scientists concerned with human and animal kidney disease.

Features

• Compares various crystallization systems
• Reviews the importance of oxalate degrading bacteria
• Discusses molecular genetics of Primary Hyperoxaluria Type I and provides strategies for replacement therapy and gene therapy
• Examines the role of all urinary macromolecules in modulating crystallization of calcium oxalate in human urine

Audience

Nephrologists, pathologists, urologists, nutritionists, veterinary pathologists, plant physiologists, biochemists, mycologists, and botanists

Contents

• Calcium Oxalate Crystallization in vitro J.P. Kavanagh
• Inhibitors of Calcium Oxalate Crystallization D.J. Kok
• Mechanisms of Calcium Oxalate Aggregation in the Biophysical Environment J.H. Adair, R.V. Linhart, C.F. Habeger, and S.R. Khan
• Calcium Oxalate Formation in Higher Plants H.T. Horner and B.L. Wagner
• Calcium Oxalate in Fungi H.J. Arnott
• Oxalate Biosynthesis and Function in Plants and Fungi V.R. Franceschi and F.A. Loewus
• Oxalate Degrading Bacteria M.J. Allison, S.L. Daniel, and N.A. Cornick
• Epidemiology of Calcium Oxalate Urolithiasis in Man D.S. Milliner
• Enzymology and Molecular Genetics of Primary Hyperoxaluria Type 1: Consequences for Clinical Management C.J. Danpure and G. Rumsby
• Cellular Abnormalities of Oxalate Transport in Nephrolithiasis B. Baggio and G. Gambaro
• Oxalate Transport Across Intestinal and Renal Epithelia M. Hatch and R.W. Freel
• Oxalate Measurement in Biological Fluids M. Marangella and M. Petrarulo
• Urinary Macromolecules in Calcium Oxalate Stone and Crystal Matrix: Good, Bad, or Indifferent R.L. Ryall and A.M.F. Stapleton
• Lipid Matrix of Urinary Calcium Oxalate Crystals and Stones S.R. Khan
• Urate and Calcium Oxalate Stones: A New Look at an Old Controversy P.K. Grover and R.L. Ryall
• The Role of Crystal-Cell Attachment and Retention in Stone Disease R.L. Hackett and P.N. Shevock
• Animal Model of Calcium Oxalate Nephrolithiasis S.R. Khan

October 1995, 400 pp., ISBN: 0-8493-7673-4
U.S. $219.00